@linux I just switched from windows 10 to Ubuntu Studio last Saturday, just wrapped up the transition yesterday. I love Linux. It is how a computer should be. I lost access to my audio interface, Keyscape VST and Valorant, but I have gained so much more. The Terminal is so much better than Windows neutered offering
Wine almost certainly won’t work for an audio interface. A lot of them use kernel drivers. When I got an M2 Mac, my audio interface didn’t work. The driver was apparently written in x86 assembly. It actually has tons of issues on ryzen CPUs as well.
After getting my M2 Mac, I upgraded to a more modern interface that doesn’t use those types of drivers, so it’s far more portable.
I don’t have a lot of experience with wine, and the experience that I have is a few years old at this point. But doesn’t it have limited compatibility with USB devices? Some audio interface are PCIe cards, but I think the vast majority are USB interfaces. That might make it complicated.
In that case I’d go for a VM, it’s chunkier but more complete than Wine will ever be.