We Just Got More Evidence That Long COVID Is a Brain Injury

The exact nature of long COVID is still coming to light, but we just got some of the best evidence yet that this debilitating condition stems from a brain injury.

Using high-resolution scanners, researchers at the Universities of Cambridge and Oxford have shown microscopic, structural abnormalities in the brainstems of those recovering from COVID-19.

Signs of brain inflammation were present up to 18 months after first contracting the SARS-CoV-2 virus.

“We show that the brainstem is a site of vulnerability to long-term effects of COVID-19, with persistent changes evident in the months after hospitalization,” the authors of the study conclude.

https://doi.org/10.1093/brain/awae215

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  • Hamartiogonic
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    10 hours ago

    Better not get vaccinated, because the vaccine kills you and covid is just another harmless flu anyway… oh wait.

    Seriously though, antivaxxers already have some sort of psychological issues going on, so adding a literal brain injury to the list might not even make a big difference at that point.

      • Hamartiogonic
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        3 hours ago

        Even lower intelligence score? As far as D&D rules are concerned, you would get knocked unconscious if your intelligence drops to zero.

        • anomnom@sh.itjust.works
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          2 hours ago

          Should probably also limit new max intelligence after you regain consciousness. That seems to be the case IRL.

          • Hamartiogonic
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            1 hour ago

            Sounds like a fun (and terrifying) idea for homebrew rules. I asked Mistral to write suitable rules, and here’s what what I ended up with.

            When a character contracts COVID-19, they must make a Constitution saving throw (DC 15). On a failed save, the character develops Long COVID. The effects of Long COVID are varied and can include fatigue, shortness of breath, and other physical ailments. However, the most feared complication is brain injury.

            Brain Injury

            Brain injury from Long COVID reduces a character’s Intelligence score. To determine the extent of the damage, the character must make a roll based on their current Intelligence score:

            Roll a d20: The result of this roll will determine the severity of the brain injury. Modify the Roll: Subtract the character’s Intelligence modifier from the roll. For example, if the character has an Intelligence score of 14 (modifier +2), subtract 2 from the d20 roll. Determine Intelligence Loss:

            • 1-5: Minor brain injury. The character loses 1 point of Intelligence.
            • 6-10: Moderate brain injury. The character loses 2 points of Intelligence.
            • 11-15: Severe brain injury. The character loses 3 points of Intelligence.
            • 16-20: Critical brain injury. The character loses 4 points of Intelligence.

            New Hard Maximum

            Once the Intelligence loss is determined, the character’s new Intelligence score becomes their hard maximum for the rest of the game. This means that even with magical healing, potions, or other means of restoring Intelligence, the character cannot exceed this new maximum.


            Oh, wait. That means that if you do drop to zero, you’ll be in permanent coma for the rest of the game without any hope of recovery. I guess I should add some exception, that allows to you recover back to 1 point, but no higher than that.

      • Hamartiogonic
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        3 hours ago

        Indeed! Too bad facts don’t work when talking to conspiracy theorists. Regardless, that’s an interesting observation to the rest of us.

    • FundMECFSResearch@lemmy.blahaj.zone
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      7 hours ago

      The majority of people with Long COVID were vaccinated. (Because the majority of people were vaccinated and vaccination only slightly reduces chances of long COVID).

      Also, many long COVID cases happened before the vaccines even came out.

      So I don’t think your attitude of victim blaming really works here.

      • Hamartiogonic
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        3 hours ago

        I guess I should have been more specific. People who actively choose not to get vaccinated, and get terribly ill as a direct result of their delusional thinking, can blame themselves.

        If you took all the sensible precautions, like getting vaccinated, but ended up with long covid regardless, that’s not your fault. You did what you could, but some times even that isn’t enough.

      • RememberTheApollo_@lemmy.world
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        5 hours ago

        What’s your point? Don’t get vaccinated because it doesn’t prevent long covid anyway? Vaccination saves lives. Period. Even your own statistic pointed out a 2% difference between vax/non-vax in getting long covid, and with hundreds of millions of covid infections every year, that 2% is a significant number of people spared long covid by vaccination.

      • Josey_Wales@lemm.ee
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        7 hours ago

        How do you know that the majority of people with Long COVID were vaccinated. This 2023 study says

        Current studies suggest that covid-19 vaccines might have protective and therapeutic effects on long covid. More robust comparative observational studies and trials are needed, however, to clearly determine the effectiveness of vaccines in preventing and treating long covid.