I usually go down the regular route a few biomes. Sometimes all the way to the temple of the art and then branch from there. Really depends on what you are going for.

Currently in my god run I’m looking for the few spells that I’m still missing for 100% progress. I already have 100% in monsters and perks. It’s just the damn fly swarm that keeps evading me. And then there’s the friend quest. I’ll put that off until I have every other spell.