• Phineaz@feddit.org
    link
    fedilink
    English
    arrow-up
    94
    ·
    2 days ago

    Toxicologists and medical scientists looking for data on humans suddenly having to learn Japanese (or German) …

  • batmaniam@lemmy.world
    link
    fedilink
    English
    arrow-up
    33
    arrow-down
    1
    ·
    2 days ago

    Similar to the meme… godamn did they fuck up by not holding geneticists to something close to… SOME standard naming.

    Dated a maternal fetal medicine specialist. She’d come home being like “you ever have to explain to someone they have a mutation in the ‘sonic the hedgehog’ gene of their kid?!” If you’re familiar with what it does in fruit flies (when it was named), it’s fucking horrific in humans. Don’t google it.

    • T156@lemmy.world
      link
      fedilink
      English
      arrow-up
      12
      ·
      22 hours ago

      It does make more sense if you consider that it is part of a line of Hedgehog genes, all of which make Fruit fly embryos look like hedgehogs (spiky) if they’re inactivated.

      They didn’t just go “Let’s name a gene with bad outcomes if mutant in humans after a video game character! Yipee! Hooray!”, at least not for that.

      Though they did name SHH’s inhibitor Robotnikin.

      • batmaniam@lemmy.world
        link
        fedilink
        English
        arrow-up
        1
        ·
        5 hours ago

        Oh I get how it got that way, it’s just unfortunate what that lead to in a clinical setting.

    • Dragon Rider (drag)@lemmy.nz
      link
      fedilink
      English
      arrow-up
      4
      arrow-down
      1
      ·
      23 hours ago

      Drag has been diagnosed with disorders that are just named after some guy, and it was boring. The kids who get told they have Sonic Hedgehog mutation are lucky. If all of our disorders had fun names, then it wouldn’t be taboo.

      • T156@lemmy.world
        link
        fedilink
        English
        arrow-up
        6
        ·
        22 hours ago

        A SHH mutation is generally not considered compatible with life. So it’s less the kids who’d find out, and more the parents.

        • Dragon Rider (drag)@lemmy.nz
          link
          fedilink
          English
          arrow-up
          5
          ·
          22 hours ago

          “Sonic Hedgehog killed my child” is a way better story than measles or leukemia. In terms of parents of dead children, those parents have it the best.

    • Toes♀@ani.social
      link
      fedilink
      English
      arrow-up
      13
      arrow-down
      1
      ·
      2 days ago

      it’s fucking horrific in humans. Don’t google it.

      Is that the R34 sonic mutation?

      • batmaniam@lemmy.world
        link
        fedilink
        English
        arrow-up
        2
        ·
        5 hours ago

        It might be? I forget exactly what it is in humans, I just remember the pictures I was shown. Midline disorders are nightmare fuel.

  • Jaderick@lemmy.world
    link
    fedilink
    English
    arrow-up
    60
    ·
    2 days ago

    Alternatively you’re asking physiology questions and the first paper that pops up is written by a 90s phrenologist whose Wikipedia page states they’re a well known white supremacist.

    Got two sentences into the abstract before stating “hol up”.