I once met a person that never drank water, only soft drinks. It’s not the unhealthiness of this that disturbed me, but the fact they did it without the requisite paperwork.

Unlike those disorganised people I have a formal waiver. I primarily drink steam and crushed glaciers.

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Joined 1 year ago
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Cake day: June 14th, 2023

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  • Sorry to hear you’re feeling crap.

    I’m having trouble looking for work for the past few months. Very few replies, the first “no” I got actually made me feel a bit more human.

    I’m convinced that some of the jobs I’ve applied for or enquired about are not real or just for external-advertising-before-hire requirements. I’ve gotten some rude responses after daring to ask questions (eg: jobs funded by research money tend to have fixed funding start dates that might not be for another several months). Most straight up ignore me.

    An old boss of mine thinks that my CV isn’t conforming and mundane enough, so I’m giving his suggestions a go.

    What sort of work are you looking at? I design electronics and get into arguments with computers.

















  • The one real risk is that it’s a respiratory depressant and that it’s LD 50 is only a few tens of times a standard dose

    The article claims it’s much closer than that:

    Experts and festival-goers agreed on the likely cause of GHB’s disproportionate overdose burden.

    “As little as 1 millilitre difference can tip you from what you’re looking for to what you’re not looking for,” Daniel Fatovich, chief investigator of EDNA, told Hack.

    I tried to find some stuff to back this up. The “therapeutic index” is probably what I’m after (ratio of effective dose to dangerous dose), despite this technically not being a therapeutic use.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843350/ - The narrow therapeutic index of GHB renders its use hazardous with poisoning or toxicity not uncommon with small titration of doses.

    Thats… annoyingly nonspecific. A number for the T.I. would be a good educational tool.

    This paper claims its around 5:1 to 8:1:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462042/ - Mortality rates after abuse of GHB are high, because there is only a narrow safety margin between a recreational dose and a fatal dose, which is only 5:1 to 8:1 [4-8]. Accordingly, accidental poisoning after recreational use of GHB is not uncommon as evidenced by admissions to hospital emergency departments for treatment [9, 10] and during forensic medical investigations of drug intoxication deaths [11-14].

    Someone else in the comments here mentioned that the recreational dosage for different individuals varies, if that’s true then it could make this worse.

    polydrug using who get hurt […] education if we want to save lives

    Agreed. Most people don’t understand what’s in pills they have bought or the interactions with alcohol.


  • I think it will take insane amounts of effort to wrangle the model into not doing its own thing. Possibly more than the amount of effort it takes to animate manually.

    “Yes this is brilliant, now generate just a few more se… why have you added a clone of my character? What? And why have the emotions on the faces of the other two swapped again? Arghh it’s confusing the subjects again! Now the room has started strobing too, goddammit this is a bathtub not a disco!”