Palworld is adding external anticheat, but it will only be required for official servers. Community servers, single player, and coop will have it be optional.
We don’t know yet if the anticheat will be compatible with Linux yet, but the options to not use it means that it shouldn’t be too disruptive either way.
I doubt it’ll work with proton but we will see. In any case I wouldn’t mind this much because they say they’ll let you disable it