Vaccines can be delivered through the skin using ultrasound. This method doesn’t damage the skin and eliminates the need for painful needles. To create a needle-free vaccine, Darcy Dunn-Lawless at the University of Oxford and his colleagues mixed vaccine molecules with tiny, cup-shaped proteins. They then applied liquid mixture to the skin of mice and exposed it to ultrasound – like that used for sonograms – for about a minute and a half.
Miniatyrize ultrasound part, make it communicare with those glucose sensors that are placed on shoulder, make it portable enough and Presto! Artificial pancreas.
Nice Idea!
Even the long application time is no issue there, since you just carry the device with you