Yes; first pull the black plastic piece out of the end of the refill. I read that there needs to be a little airflow into the refill for ink to flow, and when the back of the refill is jammed into the pen that can cut off airflow so you might cut a little notch in the end of the refill where the black plastic piece was. I also sometimes trim about 4mm off the end of the refill, or put a tiny bit of wadded paper in the pen for spacing. But I do this a little differently every time I put a new refill in.