I often take painkillers (acetaminophen aka paracetamol), but I’ve noticed that it’s much more effective if I take them TOGETHER with my ADHD medication (ritalin aka methylphenidate) + my morning coffee. If I don’t take them AT the same time, the painkiller is far less effective.

I do not exceed the maximum dosage of painkiller (1gram per intake, mornings), but alone this would barely suffice to kill my morning headache.

My hypothesis is that since the LIVER has to convert all three, I am effectively overdosing on either substance (painkiller or ADHD meds), and damaging my liver in the process.

  • Today@lemmy.world
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    6 months ago

    It’s shockingly easy to OD on acetaminophen. I don’t think you are; i just think it’s interesting how a few Tylenol plus a couple doses of cold medicine can be serious.

    • TheRealKuni@lemmy.world
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      6 months ago

      Also a fatal dose of acetaminophen/paracetamol is one of the worst ways to die. If you don’t get treatment within like, eight hours of taking it, you will slowly die of liver failure over the next few days and there’s nothing anyone can do about it. So you painfully waste away in the hospital.

      Stories of people who attempted suicide by downing a whole bottle of Tylenol are horrific, because MANY people who attempt suicide regret it after the attempt (as is reported by people who survive attempts). This means that people who attempt suicide this way still die, slowly, painfully, regretting it but unable to do anything about it, over a few days. Having to face their loved ones, knowing how hurt those loved ones are by the action. The idea terrifies me.

      Note, I am not a doctor, so take this with a grain of salt. But this is what I’ve read.

      • philpo@feddit.de
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        6 months ago

        Paramedic here who worked a lot with toxicology patients: You are entirely right.

        It’s always horrific.

      • Today@lemmy.world
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        6 months ago

        Yeah, that’s what I’ve read, a day or two of feeling shitty, a day of feeling better and been dead.