Especially if you have a chronic disease, I have non stop headeachs but a great boss and I’m a programmer (more flexibility), and man a day off or work from home, every 1-3 weeks are a god send. You don’t even realise how bad you actually feel until you take a moment to breeth. My boss actually made me take my first day off when he saw how bad I looked and mental healthcare has been my priority ever since. Never forget to take care of your body AND mind.