I did some digging and can’t for the life of me find that clinical trial I was thinking of so I might just be remembering it wrong, but I do know there’s a lot of interest in parasite-derived immunomodulatory molecules, which interestingly do often seem to be derived from helminth excretions or secretions.
a) Thank you! That was super sweet! No worries, I legit pick up and put down stuff all over the place. So the crossed wires are immense.
b) I went through a series of emotiosn reading about helminth treatment. Thought: “how far are you willing to push to get better? Would I do this? Yes? No? Maybe so. Eh!” I think even the journal itself notes that it’s a relatively common reaction to this new form of treatment. But if they could figure out how to spin this large scale over time, nobody really needs to know what the source of the extract is. Just more so that it can reduce swelling and seems to be hypoallergenic. Which would be pretty rad in my book. Not so open to a pill of worms in my body, way more open to treatment derived from their lipids.
But yeah I think derived drugs are the way to go in the long run, infecting someone with actual parasites can be a bit of a can of worms (pun intended) although not nearly as bad as it sounds like
Hahaha! You got me laughing over here! Hahaha! Yeah it sounds like it helped some, but hindered others. And in general is pretty unpredictable. But like I said, when you’re in a desperate (hopeless) situation it’s kinda like…what line are you willing to cross in order to get better? Stinks, but it does go through the old brian-bin.
I did some digging and can’t for the life of me find that clinical trial I was thinking of so I might just be remembering it wrong, but I do know there’s a lot of interest in parasite-derived immunomodulatory molecules, which interestingly do often seem to be derived from helminth excretions or secretions.
This 2022 Frontiers in Parasitology article titled Immunomodulatory and biological properties of helminth-derived small molecules: Potential applications in diagnostics and therapeutics seems like a good review of the current situation.
a) Thank you! That was super sweet! No worries, I legit pick up and put down stuff all over the place. So the crossed wires are immense.
b) I went through a series of emotiosn reading about helminth treatment. Thought: “how far are you willing to push to get better? Would I do this? Yes? No? Maybe so. Eh!” I think even the journal itself notes that it’s a relatively common reaction to this new form of treatment. But if they could figure out how to spin this large scale over time, nobody really needs to know what the source of the extract is. Just more so that it can reduce swelling and seems to be hypoallergenic. Which would be pretty rad in my book. Not so open to a pill of worms in my body, way more open to treatment derived from their lipids.
Thanks again!
You’re welcome!
But yeah I think derived drugs are the way to go in the long run, infecting someone with actual parasites can be a bit of a can of worms (pun intended) although not nearly as bad as it sounds like
Hahaha! You got me laughing over here! Hahaha! Yeah it sounds like it helped some, but hindered others. And in general is pretty unpredictable. But like I said, when you’re in a desperate (hopeless) situation it’s kinda like…what line are you willing to cross in order to get better? Stinks, but it does go through the old brian-bin.